Bioinformatics

Bioinformatics Engineer Jobs

3 jobs found

Today

Bioinformatics Software Engineer III, OncoKB

Memorial Sloan Kettering Cancer Center New York, NY

New York, NY

Today

$124k - $205k/yr Full time Backend Developer APIs Application Security

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Job Description

Memorial Sloan Kettering Cancer Center is hiring a Bioinformatics Software Engineer III, OncoKB to support precision oncology through software that advances cancer genomics research and clinical care. In this hybrid role in New York, you will design, build, and improve scalable applications and the supporting API and database infrastructure, while working through complex technical challenges.

What you’ll do

Create comprehensive system designs that help the OncoKB platform scale and evolve over time.
Collaborate closely with the Lead Software Engineer and cross-functional teams of software engineers, scientists, and clinicians.
Develop and enhance front-end and back-end applications for genomic analysis, content curation, and clinical annotation workflows.
Support the ongoing growth of the OncoKB website, API, and underlying database infrastructure.
Troubleshoot and resolve complex software issues in a fast-paced environment.
Mentor junior developers and reinforce engineering best practices across the team.

Minimum qualifications

Bachelor’s degree in Computer Science, Bioinformatics, or a related field, or equivalent practical experience through a coding bootcamp and professional development.
4+ years of full-stack web development experience.
Experience building and supporting production-level software applications.
Strong written and verbal communication skills and the ability to collaborate with technical and non-technical stakeholders.
Interest in learning cancer biology, genomics, and precision medicine applications.

Core skills and technologies

JavaScript/TypeScript
React, HTML, CSS
Server-side experience with one or more of: Go, Java, C#, C++, Python
Relational databases including MySQL or PostgreSQL
Git/GitHub or similar source control
Full-stack application architecture and development
Systems design and software troubleshooting

Additional technology exposure

Familiarity with Docker and containerized application development
Experience with Kubernetes and/or AWS cloud environments
Coursework or professional experience in biology, genetics, genomics, or bioinformatics
Interest in server-side rendered web development, including experience with or willingness to learn Datastar
Interest in Go development as the platform expands toward new Go-based services

Role details

Location: 323 E. 61st Street, NYC (Mackowe)
Work model: Hybrid, in office once a week, M-F, 37.5 hours
Reporting to: Bioinformatics Software Engineer IV

Compensation

USD 124,000 - 204,700 per year.

Helpful resources are available via the Compensation Philosophy and Benefits links.

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1mo ago

Sr. Software Engineer, Bioinformatics

Quest Diagnostics West Norriton, PA

West Norriton, PA

1mo ago Closed

Full time Backend Developer Senior API

This position is no longer accepting applications (closed Oct 24, 2026).

Job Description

The Sr. Software Engineer, Bioinformatics role focuses on building and supporting full stack applications that work with genetic data. The position combines software engineering, data workflow development, and API implementation within an enterprise environment, with deployment responsibilities and active participation in agile delivery.

Role Overview

Design, implement, and maintain software applications used to process and support genetic data. This role includes creating complex data workflows and pipelines, building RESTful/JSON-based services, and deploying applications in the cloud to support scalability and reliability.

Key Responsibilities

Design, implement, and maintain software applications.
Ensure solutions meet user requirements and performance standards.
Develop complex data workflows, pipelines, and RESTful/JSON-based APIs in an enterprise setting.
Deploy and manage applications to improve scalability and reliability.
Participate in agile activities, including sprint planning, daily stand-ups, and retrospectives.
Collaborate with cross-functional teams to support seamless integration and delivery.
Write automated unit, integration, and end-to-end tests to maintain code quality.
Conduct peer code reviews to support development standards.

Required Qualifications

3+ Years of relevant experience.
Proficiency in modern software development practices and tools, including CI/CD pipelines, version control, and testing frameworks.
Demonstrated experience designing and orchestrating complex data workflows, pipelines, and RESTful/JSON-based APIs.
Experience with PHP, Laravel, MySQL, REACT.
Familiarity with agile methodologies.
Test-driven development mindset with experience writing tests.
Excellent communication skills to coordinate with technical and non-technical stakeholders.

Preferred Qualifications

Knowledge of the health industry or interest in genetics and bioinformatics.
Experience implementing solutions in the cloud, with AWS preferred.
Experience designing and working with application programming interfaces, including JSON-based RESTful APIs.

Technologies

PHP
Laravel
MySQL
REACT
RESTful
JSON

Collaboration and Availability Requirements

This role requires collaboration with teams in the US and EU. An overlap of at least 2 hours during business hours is expected.

Education

Bachelor’s degree in Computer Science, Engineering, or a related field (required).
Master’s degree in Computer Science, Engineering, or a related field (preferred).

Additional Knowledge and Skills

Proficiency in full stack development, including front-end, back-end, and databases.
Strong problem-solving skills and a commitment to continuous learning.
Demonstrated proficiency and experience in the health care industry or life sciences.
Adaptability to new tools and technologies.

Location and Work Setting

West Norriton, PA (onsite)

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3mo ago

Senior Bioinformatics Data Engineer

Kaztronix Wilmington, DE

Wilmington, DE

3mo ago Closed

Full time Senior Bioinformatics Data

This position is no longer accepting applications (closed Aug 2, 2026).

Job Description

Kaztronix seeks a Senior Bioinformatics Data Engineer for an onsite role in Wilmington, Delaware, to drive the modernization of a biomarker data lake on AWS. This position focuses on building and operating production pipelines across oncology clinical studies, partnering with the lead engineer across the full tech stack, and enabling downstream AI and visualization workflows with a strong emphasis on reproducibility and reliability.

Responsibilities

Design and maintain ingestion pipelines orchestrated by Dagster for genomics vendors such as Caris, Predicine, Tempus, Olink, and CellCarta, incorporating IO managers, Iceberg writers, and row‑level accounting.
Advance dbt Silver‑to‑Gold transformations with real data test coverage, store‑failures patterns, staging/intermediate/mart models, and macro consolidation.
Build clinical data ingestion paths for SDTM and ADaM, implement reconciliation logic, and route subject dimensions as required.
Deliver platform infrastructure including FastAPI endpoints, CI/CD pipelines, containerized deployments, observability instrumentation, and performance tuning for Redshift.
Extract and reconcile transformation rules from legacy R and PySpark code against new platform implementations to maintain fidelity.
Identify repetitive processes and convert them into automated workflows, guardrails, or reusable tooling to improve efficiency and consistency.
Participate in adversarial design and code reviews, pinpoint edge cases, and push back on suboptimal patterns.
Collaborate with the lead engineer on design decisions and maintain delivery velocity through paired working sessions and pull request reviews.
Ensure reproducibility standards are met across the codebase with CI on every PR, automated tests, and avoidance of ad hoc notebook‑based production processes.

Requirements

AI‑native engineering practice: proven experience building systems and workflows around AI coding agents such as Claude Code, Cursor, Codex, or equivalent. This goes beyond using prompts alone; you know when to automate, implement guardrails, and construct infrastructure that speeds future work.
Education: Bachelor's or master's degree in computer science, data engineering, bioinformatics, or a related field.
Experience: at least 5 years of professional data engineering experience delivering production pipelines on AWS (S3, ECS/Fargate, Redshift or equivalent MPP).
Strong Python and SQL skills with working knowledge of modern data engineering libraries.
Advanced proficiency with dbt and a workflow orchestration tool such as Dagster, Airflow, or Prefect.
Data quality instinct: track record of catching silent failures, questioning data correctness, and identifying lossy joins or incomplete deliveries.
Solid understanding of lakehouse architectures, ETL processes, and schema design for complex multi‑modal datasets.
Ability to handle PHI‑adjacent clinical data under contractor policy, including background checks, compliance training, and VPN access.
Willingness to work with legacy codebases (R, PySpark) to extract business rules and validate new implementations.
Excellent communication skills and experience working in an embedded pair model with tight feedback loops.

Technologies

Dagster
dbt
Apache Iceberg
Amazon S3
Redshift
FastAPI
Docker
Amazon ECS
AWS Fargate
Python
SQL
R
PySpark
Airflow
Prefect
CloudFormation
AWS Glue Catalog
CI/CD

Preferred Qualifications

Direct experience with Apache Iceberg, AWS Glue Catalog, or lakehouse table formats.
Comfort reading genomic data such as VAF, HGVS nomenclature, VCFs, CNV/fusion semantics, or the ability to ramp quickly on unfamiliar scientific domains.
Familiarity with SDTM, ADaM, and CDISC clinical data standards.
Pharma, clinical research, or life sciences background.
Experience with containerization (Docker/ECS) and infrastructure as code (CloudFormation).
Proficiency in R for interoperability with bioinformatics teams.

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Bioinformatics Engineer Jobs

Bioinformatics Software Engineer III, OncoKB

Sr. Software Engineer, Bioinformatics

Senior Bioinformatics Data Engineer

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