Biotech Pharma

Biotech Pharma Engineer Jobs

2 jobs found

23d ago

Senior Specialist: Data Engineer for Upstream Biologics

Merck Boston, MA

Boston, MA

23d ago

$117k - $184k/yr Full time Python Senior Analytics

Apply Now

Job Description

Location: Boston, MA onsite with hybrid options. Merck offers a collaborative, inclusive culture and a comprehensive benefits package for a Senior Specialist, Data Engineer focused on Upstream Biologics. This role centers on designing and maintaining data pipelines to ingest Upstream Biologics Process Development data, enabling downstream analytics, process characterization, scale-up predictions, and multivariate analyses.

Benefits

Medical, dental, and vision coverage for employees and their families
Retirement benefits, including a 401(k) plan
Paid holidays
Vacation time
Compassionate and sick days

Responsibilities

Build and maintain robust, scalable data pipelines that ingest experimental and process data from upstream biologics source systems
Deliver analysis-ready datasets to support upstream digital initiatives, including process characterization models, scale-up predictions, multivariate analytics, and high throughput process development workflows
Map instrument outputs and experimental results ensuring ontology alignment and interoperability across upstream data sources
Develop and maintain data visualizations, dashboards, and reports that enable upstream scientists to explore process data across runs, molecules, and scales
Support system of record standards by ensuring consistent data entry practices
Identify and flag data quality issues, gaps in metadata, and inconsistencies across source systems, contributing to continuous improvement of upstream data capture practices
Collaborate with upstream process development scientists, analytical scientists, and engineers to understand evolving data needs and translate them into pipeline requirements
Coordinate with adjacent domain engineers to ensure seamless data handoffs at domain boundaries
Maintain and version all pipeline code in GitHub, following team standards for code review, documentation, and deployment
Demonstrate excellent interpersonal, communication, and collaboration skills
Embrace and model our core values of inclusion, including fostering a supportive culture where all can thrive
Collaborate effectively in a dynamic, integrated, and multidisciplinary team environment

Requirements

PhD required; minimum 2 years of experience
Proficient in Python and/or R programming
Comfortable in development environments such as Jupyter, Posit/RStudio, or VS Code
Solid SQL skills with hands-on experience writing and optimizing queries against relational databases and data warehouses
Experience with ETL/ELT processes and building data pipelines in a scientific or pharmaceutical context
Familiarity with version control systems (Git/GitHub) and collaborative software development practices
Ability to work in a team environment with cross-functional interactions
Motivated to learn new skills, willing to take on new challenges, and scientifically curious

Technologies

Python, R
Jupyter, Posit/RStudio, VS Code
SQL, Git, GitHub
Databricks, Delta Lake
Streamlit, Shiny
PowerBI, Spotfire, Tableau
Allotrope Simple Model, ISA-88, OPC-UA

Posting details

Requisition ID: R404620
End date: 07/9/2026
Location: Boston, MA (onsite) with Hybrid arrangements
Employee status: Regular

Inclusion, accommodations, and fair hiring

Merck supports inclusive hiring and will consider qualified applicants including those with arrest or conviction records in compliance with applicable laws. For accommodation during the application or hiring process, please request assistance. We observe fair chance hiring practices in accordance with local ordinances where applicable.

Additional notes

Posting is active through the stated end date above. This role emphasizes collaboration across upstream process development, analytical science, and engineering teams to meet evolving data needs.

View full job page →

2mo ago

Associate Engineer, RNA Starting Material MS&T

Sarepta Therapeutics Andover, MA

Andover, MA

2mo ago Closed

$62k - $78k/yr Full time Biotech Pharma Engineering Manufacturing

This position is no longer accepting applications (closed Jun 16, 2026).

Job Description

The Associate Engineer, RNA Starting Material MS&T role at Sarepta Therapeutics in Andover, MA focuses on supporting synthesis, purification, analysis, and characterization of nucleoside-based and lipid building blocks for PMOs, next-generation PMO, and siRNA platforms, with involvement in development, scale-up, and tech transfer of RNA starting materials manufacturing.

Responsibilities

Collaborate in a team performing lab-scale organic synthesis, purification, analysis, and characterization of nucleoside-based and lipid building blocks used in Sarepta's PMO, next-gen PMO, and siRNA platforms.
Prepare reference markers and standards and contribute to supervised RNA starting materials manufacturing process chemistry development and scale-up projects to optimize routes and troubleshoot syntheses.
Engage in cross-functional training, coordinate with Analytical/QC resources, and interpret data from HPLC, GC, KF, and NMR analyses.
Draft experimental protocols and generate technical reports, applying strong organic chemistry knowledge and problem-solving skills.

Requirements

Bachelor of Science in Chemical Engineering, Chemistry, or a related discipline, with 0-2 years of relevant experience.
Solid grounding in organic chemistry and the ability to interpret data from GC, LC-MS, HPLC, NMR, and KF; practical experience running HPLC methods is strongly preferred.
Ability to manage multiple tasks and meet deadlines in a fast-paced environment.
Effective written and verbal communication skills.
Strong interpersonal skills and meticulous attention to detail.
May require up to 5% travel, domestically or internationally.

Technologies

HPLC
GC
LC-MS
NMR
KF

Benefits

Physical and Emotional Wellness
Financial Wellness
Support for Caregivers

The Importance of the Role

Supports lab-scale synthesis, purification, analysis, and characterization of nucleoside-based and lipid building blocks for PMOs, next-generation PMO, and siRNA platforms.
Contributes to the synthesis of reference markers and participates in supervised RNA starting materials process chemistry development and scale-up to optimize syntheses.
Involves cross-functional training and regular collaboration with Analytical/QC teams, including interpretation of HPLC, GC, KF, and NMR data.
Includes protocol writing and report generation, requiring strong organic chemistry and problem-solving capabilities.

The Opportunity to Make a Difference

Support commercial supply assurance for RNA starting materials by synthesizing nucleoside reference markers and standards.
Execute development studies independently or as part of a supervised team.
Assess scalability of proposed changes and run experiments to mimic large-scale operations.
Participate in technology transfer of improved processes to manufacturing sites.
Build a solid understanding of Sarepta’s manufacturing processes to support process improvements, troubleshooting, and technology transfers.
Perform synthesis and purification of nucleoside analogs to support production and development goals.
Contribute to impurity profiling and collaborative efforts to characterize and manage impurities in intermediates.
Use scientific judgment to identify likely sources of impurities and design experiments to test hypotheses within cross-functional teams.
Compile data, interpret results, document study outcomes, and present conclusions.
Attend vendor update meetings and provide input on ongoing vendor production projects.

More About You

Bachelor of Science in Chemical Engineering, Chemistry, or related discipline, 0-2 years of experience.
Technical competence in organic chemistry and familiarity with GC, LC-MS, HPLC, NMR, and KF data; experience running HPLC methods preferred.
Able to multitask and meet deadlines in a dynamic setting.
Strong written and verbal communication skills.
Excellent interpersonal skills and careful attention to detail.
May require travel up to 5 percent of time, domestically or internationally.

View full job page →

Biotech Pharma Engineer Jobs

Senior Specialist: Data Engineer for Upstream Biologics

Associate Engineer, RNA Starting Material MS&T

Get Biotech Pharma Engineer Jobs alerts